JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Journal of The American Chemical Society

Calcium directly regulates phosphatidylinositol 4,5-bisphosphate headgroup conformation and recognition

Bilkova E.*, Pleskot R.*, Rissanen S.*, Sun S.*, Czogalla A., Cwiklik L., Rog T., Vattulainen I., Cremer P.S.‡, Jungwirth P.‡, Coskun Ü.‡. *These authors contributed equally to this work ‡Corresponding authors
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 139 : 4019-4024 , 2017
Keywords: PI(4,5)P2, phosphoinositides, Lipid electrostatics, Lipid signaling, Membrane binding, PH domain, calcium, MD simulation, Sum-frequency generation spectroscopy