Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
graduated technical assistant
- Jitka Hansgutová DiS.
- In 21st Conference on Isoprenoids. Bialystok : University of Bialystok (2005) 94 2005
- In 21st Conference on Isoprenoids. Bialystok : University of Bialystok (2005) 96 2005
- In 21st Conference on Isoprenoids. Bialystok : University of Bialystok (2005) 97 2005
Separation, characterization, and quantitation of phenolic acids in a little-known blueberry (Vaccinium arctostaphylos L.) fruit by HPLC-MSJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 51  8116-8122 2005
The involvement of cytokinin oxidase/dehydrogenase and zeatin reductase in regulation of cytokinin levels in pea (Pisum sativum L.) leavesJOURNAL OF PLANT GROWTH REGULATION 24 188-200 2005
- PLANT GROWTH REGULATION 47  1-7 2005
- ZEITSCHRIFT FUER NATURFORSCHUNG. SECTION C: A JOURNAL OF BIOSCIENCES 60c [11/12] 876-882 2005
- CHEMICKÉ LISTY 98  834-841 2004
- EUROPEAN JOURNAL OF BIOCHEMISTRY 271  3990-4002 2004
Screening microalgae for some potentially useful agricultural and pharmaceutical secondary metabolitesJOURNAL OF APPLIED PHYCOLOGY 16  309-314 2004