In vitro anti-microbial activity of extracts from the callus cultures of some Nigella species

Landa P., Maršík P., Vaněk T., Rada V., Kokoška L.
BIOLOGIA 61 [3]: 285-288, 2006

Keywords: Nigella - callus culture - antimicrobial activity
Abstract: Crude methanol extracts from callus cultures of Nigella arvensis, N. damascena, N. hispanica, N. integrifolia, and N. sativa were investigated for their anti-microbial activity. Growth inhibition was determined in Gram-positive and Gram-negative bacterial strains as well as in yeast by using a broth-microdilution method. The results showed that the extracts of all calli tested exhibited significant anti-microbial activity, especially against Bacillus cereus, Staphylococcus aureus and Staphylococcus epidermidis. Compared with other Nigella species, a callus culture of N. hispanica was the most effective against the microorganisms used in this study.
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IEB authors: Přemysl Landa, Petr Maršík, Tomáš Vaněk