Laboratoř růstových regulátorů
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
Pracovníci
- Mgr Tomáš Vlčko
vedoucí skupinyvedoucí vědecký pracovník
- Prof. Mgr. Ondřej Novák Ph.D.
zástupce vedoucího laboratořevědecký pracovník
- Prof. ing. Miroslav Strnad CSc.
vedoucí vědecký pracovník
vědecký pracovník
- RNDr. Martin Fellner Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- doc. Mgr. Danuše Tarkowská Ph.D.
vědecký asistent
odborný pracovník
- Mgr. Ota Blahoušek
- Ing. Věra Doleželová
- Mgr. Pavel Jaworek Ph.D.
- Ivan Petřík
postdoktorand
sekretářka-asistentka
- Jitka Hansgutová DiS.
údržba
Výzkumné projekty
- Biosyntéza a signalizace u giberelinů - identifikace nových cílů pro regulaci růstu rostlin , GA ČR , Peter Hedden
- Syntéza nových brassinosteroidů a studium jejich interakce s rostlinnými a živočišnými receptory , GA ČR , Miroslav Kvasnica
- Cílené metabolické profilování rostlinných růstových regulátorů , MŠMT , Ondřej Novák
Publikace
2022
- BMC PLANT BIOLOGY 22 284 2022 (External fulltext)
- PLANT PHYSIOLOGY 187 103-115 2022
2021
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021 (External fulltext)
- NATURE PLANTS 7 619-623 2021
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 2855 2021
- BIOMOLECULES 11 553 2021
-
Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side ChainINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 155 2021
- BIOMOLECULES 11 27 2021
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 2021
- MOLECULES 26 1173 2021