The plant non-specific phospholipase C gene family. Novel competitors in lipid signalling

Pokotylo I., Pejchar P., Potocký M., Kocourková D., Krčková Z., Ruelland E., Kravets V., Martinec J.

Keywords: Plant nonspecific phospholipase C, phosphatidylcholine-specific phospholipase C, diacylglycerol, cell signaling, metabolism regulation
Abstract: Non-specific phospholipases C (NPCs) were discovered as a novel type of plant phospholipid-cleaving enzyme homologous to bacterial phosphatidylcholine-specific phospholipases C and responsible for lipid conversion during phosphate-limiting conditions. AThe six-gene family was established in Arabidopsis, and growing evidence suggests the involvement of NPCs in biotic and abiotic stress responses as well as phytohormone actions. In addition, the diacylglycerol produced via NPCs is postulated to participate in membrane remodelling, general lipid metabolism and cross-talk with other phospholipid signalling systems in plants. This review summarises information concerning this new plant protein family and focusses on its sequence analysis, biochemical properties, cellular and tissue distribution and physiological functions. Possible modes of action are also discussed.
DOI: IEB authors: Daniela Kocourková, Zuzana Krčková, Jan Martinec, Přemysl Pejchar, Martin Potocký