Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- doc. Mgr. Ondřej Novák Ph.D.
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- Prof. ing. Miroslav Strnad CSc.
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
graduated technical assistant
Molecular mechanisms and hormonal regulation underpinning morphological dormancy: a case study using Apium graveolens (Apiaceae)PLANT JOURNAL 2021 (External fulltext)
- JOURNAL OF EXPERIMENTAL BOTANY 72 355-370 2021 Fulltext: public PDF link
- BIOMOLECULES 11 24 2021 Fulltext: PDF link on intranet only
- ENVIRONMENTAL AND EXPERIMENTAL BOTANY 182 104295 2021
Lycopene β-cyclase expression influences plant physiology, development and metabolism in tobacco plantsJOURNAL OF EXPERIMENTAL BOTANY 2021 (External fulltext)
Naturally Occurring Ecdysteroids in Triticum aestivum L. and Evaluation of Fenarimol as a Potential Inhibitor of Their Biosynthesis in PlantsINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2021 (External fulltext)
Naturally Occurring Ecdysteroids in Triticum aestivumL. and Evaluation of Fenarimol as a Potential Inhibitor of Their Biosynthesis in PlantsINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 2855 2021
- CURRENT BIOLOGY 2021 (External fulltext)
Inhibition of gibberellin accumulation by water deficiency promotes fast and long-term 'drought avoidance' responses in tomatoNEW PHYTOLOGIST 232 1985-1998 2021 (External fulltext)
Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side ChainINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 155 2021