Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- doc. Mgr. Ondřej Novák Ph.D.
deputy head of the laboratoryscientist
- Prof. ing. Miroslav Strnad CSc.
A Differential Phytohormone Profile in the Aerial Part and Roots as a Response to Water Stress Underlying Morphophysiological and Biochemical Changes in Two Inbred Sunflower Lines at Early Growth StageJOURNAL OF PLANT GROWTH REGULATION 2023
Phytochromes mediate germination inhibition under red, far-red, and white light in Aethionema arabicumPLANT PHYSIOLOGY 2023
Small Change – Big Consequence: The Impact of C15-C16 Double Bond in a D ring of Estrone on Estrogen Receptor ActivityJOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 233 106365 2023
Distinct hormonal and morphological control of dormancy and germination in Chenopodium album dimorphic seedsFRONTIERS IN PLANT SCIENCE 14 1156794 2023 (External fulltext)
Urea derivate MTU improves stress tolerance and yield in wheat by promoting cyclic electron flow around PSIFRONTIERS IN PLANT SCIENCE 14 1131326 2023 (External fulltext)
- JOURNAL OF PLANT GROWTH REGULATION 42 2519–2529 2023 (External fulltext)
Hormone profiling and the root proteome analysis of itpk1 mutant seedlings of barley (Hordeum vulgare) during the red-light induced photomorphogenesisENVIRONMENTAL AND EXPERIMENTAL BOTANY 213 105428 2023 (External fulltext)
- PLANT JOURNAL 115 470-479 2023 (External fulltext)
CRISPR/Cas9 genome-editing applied to MdPGT1 in apple results in reduced foliar phloridzin without impacting plant growthPLANT JOURNAL 113 92-105 2023 (External fulltext)
Contents of endogenous brassinosteroids and the response to drought and/or exogenously applied 24-epibrassinolide in two different maize leavesFRONTIERS IN PLANT SCIENCE 14 2023 (External fulltext)