Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
graduated technical assistant
- Jitka Hansgutová DiS.
Molecular mechanisms of plant steroids and study of their interaction with nuclear receptors in prostate cancer cellsFOOD AND CHEMICAL TOXICOLOGY 137 2020
- FRONTIERS IN PLANT SCIENCE 11 736 2020 (External fulltext)
Phytohormone profile and CiFL1 expression in young seedlings of Cichorium intybus L. var sativum exposed to high temperature in relation to vernalization and de-vernalization processesENVIRONMENTAL AND EXPERIMENTAL BOTANY 2020 (External fulltext)
A Fast and Reliable UHPLC–MS/MS-Based Method for Screening Selected Pharmacologically Significant Natural Plant Indole AlkaloidsMOLECULES 25 3274 2020 (External fulltext)
Phytohormone profile and CiFL1 expression in young seedlings of Cichorium intybus L. var sativum exposed to high temperature in relation to vernalization and de-vernalization processesENVIRONMENTAL AND EXPERIMENTAL BOTANY 178 104127 2020 Fulltext: PDF link on intranet only
- BMC PLANT BIOLOGY 19 112 2019 (External fulltext)
- 8 78 2019 (External fulltext)
Early Brassica crops responses to salinity stress: a comparative analysis between Chinese cabbage, white cabbage and kaleFRONTIERS IN PLANT SCIENCE 2019 (External fulltext)
- JOURNAL OF EXPERIMENTAL BOTANY 2019 (External fulltext)
Effect of gibberellins on growth and biochemical constituents in Chlorella minutissima (Trebouxiophyceae)SOUTH AFRICAN JOURNAL OF BOTANY 2019 (External fulltext)