Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
graduated technical assistant
- Jitka Hansgutová DiS.
- Applied Plant Biotechnology for Improving Resistance to Biotic Stress 1st Edition 2019
Quantification of karrikins in smoke water using ultra-high performance liquid chromatography–tandem mass spectrometryPLANT METHODS 15 81 2019 (External fulltext)
Changes in content of steroid regulators during cold hardening of winter wheat - steroid physiological/biochemical activity and impact on frost resistancePLANT PHYSIOLOGY AND BIOCHEMISTRY 139 215-228 2019 (External fulltext)
A DAO1-mediated circuit controls auxin and jasmonate crosstalk robustness during adventitious root initiation in ArabidopsisINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 4428 2019 (External fulltext)
Effects of potato spindle tuber viroid infection on phytohormone and antioxidant responses in symptomless Solanum laxum plantsJOURNAL OF PLANT GROWTH REGULATION 38 325–332 2019 (External fulltext)
Organ-specific differences in endogenous phytohormone and antioxidative responses in potato upon PSTVd infectionJOURNAL OF PLANT PHYSIOLOGY 232 107–114 2019 (External fulltext)
- PLANT PROTECTION SCIENCE 55 31–42 2019 (External fulltext)
Mutations in the HvDWARF, HvCPD and HvBRI1 genes-involved in brassinosteroid biosynthesis/signalling: Altered photosynthetic efficiency, hormonal homeostasis and tolerance to high/low temperatures in barleyJOURNAL OF PLANT GROWTH REGULATION 38 1062–1081 2019 (External fulltext)
Surveillance of cell wall diffusion barrier integrity modulates water and solute transport in plantsSCIENTIFIC REPORTS 9 4227 2019 (External fulltext)
- Floriculture Ornamental and Plant biotechnology: Advances and Topical Issues (1st edition) 2019