Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and Institute of Experimental Botany, Academy of Sciences of the Czech Republic (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc., Ing. Jan Krekule DrSc.
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- doc. Mgr. Ondřej Novák Ph.D.
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Mgr. Lucie Plíhalová Ph.D.
- Jiří Pospíšil
- Jitka Široká
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
graduated technical assistant
- Jitka Hansgutová DiS.
Altered expression of maize PLASTOCHRON1 enhances biomass and seed yield by extending cell division duration.NATURE COMMUNICATIONS 8 14752 2017
- JOURNAL OF PLANT PHYSIOLOGY 214 53-63 2017 (External fulltext)
Microscale magnetic microparticle-based immunopurification of cytokinins from Arabidopsis root apex.PLANT JOURNAL 85 1065-1075 2017
Immunoaffinity chromatography combined with tandem mass spectrometry: A new tool for the selective capture and analysis of brassinosteroid plant hormones.TALANTA 170 432-440 2017
Synthesis of novel aryl brassinosteroids through alkene cross-metathesis and preliminary biological study.STEROIDS 2017
Biochemical and Physicochemical Background of Mammalian Androgen Activity in Winter Wheat Exposed to Low Temperature.JOURNAL OF PLANT GROWTH REGULATION 2017
- Mechanisms behind phytohormonal signalling and crop abiotic stress tolerance 265-279 2017
- PLoS ONE 12 e0170715 2017 (External fulltext)
The DAG1 transcription factor negatively regulates the seed-to-seedling transition in Arabidopsis acting on ABA and GA levelsBMC PLANT BIOLOGY 16 198 2016 (External fulltext)
A previously undescribed jasmonate compound in flowering Arabidopsis thaliana - The identification of cis-(+)-OPDA-IlePHYTOCHEMISTRY 230-237 2016 (External fulltext)