Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- doc. Mgr. Ondřej Novák Ph.D.
deputy head of the laboratoryscientist
- Prof. ing. Miroslav Strnad CSc.
- RNDr. Martin Fellner Ph.D.
- Jiří Grúz
- Doc. RNDr. Vladimír Kryštof Ph.D.
- RNDr. Miroslav Kvasnica Ph.D.
- Mgr. Marie Kvasnicová
- Ing. Ludmila Ohnoutková Ph.D.
- Mgr. Jana Oklešťková PhD.
- Jiří Pospíšil
- Jitka Široká
- Mgr. Danuše Tarkowská Ph.D.
- Jiří Voller
- Michaela Mrvková
- Mgr. Lukáš Spíchal Ph.D.
graduated technical assistant
- Jitka Hansgutová DiS.
- Mgr. Pavel Jaworek Ph.D.
A mitochondrial ADXR-ADX-P450 electron transport chain is essential for maternal gametophytic control of embryogenesis in ArabidopsisPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES 119 e2000482119 2022 (External fulltext)
Salt-specific gene expression reveals elevated auxin levels in Arabidopsis thaliana plants grown under saline conditionsFRONTIERS IN PLANT SCIENCE 13 804716 2022 (External fulltext)
The photoperiod stress response in Arabidopsis thaliana depends on auxin acting as an antagonist to the protectant cytokininINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 2936 2022 (External fulltext)
- FRONTIERS IN PLANT SCIENCE 13 844292 2022 (External fulltext)
CLAVATA modulates auxin homeostasis and transport to regulate stem cell identity and plant shape in a mossNEW PHYTOLOGIST 234 149-163 2022 (External fulltext)
Changing temperature conditions during somatic embryo maturation result in Pinus pinaster plants with altered response to heat stressINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 1318 2022 (External fulltext)
- CURRENT BIOLOGY 32 1764-1775.e3 2022 (External fulltext)
- MOLECULAR PLANT 15 322-339 2022 (External fulltext)
Changes in the concentrations and transcripts for gibberellins and other hormones in a growing leaf and roots of wheat seedlings in response to water restrictionBMC PLANT BIOLOGY 22 284 2022 (External fulltext)
- PLANT PHYSIOLOGY 187 103-115 2022