Laboratory of Growth Regulators
Laboratory of Growth Regulators has been created in 1995 as a joined facility of the Faculty of Science, Palacký University (www.upol.cz) and the Institute of Experimental Botany of the Czech Academy of Sciences (www.ueb.cas.cz).
Research program of the laboratory is aimed primary at small molecules that regulate cell division cycle, proliferation and growth of both plant and animal cells. Namely cytokinins and cytokinin-derived purine inhibitors of cyclin-dependent kinases belongs to the most intensively studied compounds. The representative of the latter, roscovitine (CYC202, seliciclib), already undergoes phase II clinical trials in patients as a novel anticancer drug held by Cyclacel Ltd (for more information see actual Press Release).
Our multidisciplinary research team is composed of experienced plant physiologists, biochemists as well as organic and analytical chemists. Many students are involved in the research during their pregradual and postgraduate studies of botany, analytical and organic chemistry, biochemistry or medicinal biology, respectively.
Laboratory of Growth Regulators guarantees the teaching for biological study programs. Members of the laboratory give lectures from general botany, plant physiology, microbiology, chemistry, molecular biology, including practical courses and seminars.
Several reseach projects are in progress in colaboration with international partners (University of Berlin, Germany; Swedish University of Agricultural Sciences, Sweden; University of Natal Pietermaritzburg, South Africa; Vienna Medical University, Austria).
head of the laboratorysenior scientist
- Prof. ing. Miroslav Strnad CSc.
graduated technical assistant
- Jitka Hansgutová DiS.
The cytokinin complex associated with Rhodococcus fascians: which compounds are critical for virulence?FRONTIERS IN PLANT SCIENCE 10 674 2019 (External fulltext)
How do different watering regimes affect the growth, chlorophyll fluorescence, phytohormone and phenolic acid content of greenhouse-grown Ceratotheca triloba?JOURNAL OF PLANT GROWTH REGULATION 38 385–399 2019 (External fulltext)
Elucidating the role of Kelpak® on the growth, phytohormone composition, and phenolic acids in macronutrient-stressed Ceratotheca triloba.JOURNAL OF APPLIED PHYCOLOGY 31 2687–2697 2019 (External fulltext)
Root enhancement in cytokinin-deficient oilseed rape causes leaf mineral enrichment, increases the chlorophyll concentration under nutrient limitation and enhances the phytoremediation capacityBMC PLANT BIOLOGY 19 83 2019 (External fulltext)
- PLANTS 8 78 2019 (External fulltext)
Production and role of hormones during interaction of Fusarium species with maize (Zea mays L.) seedlingsFRONTIERS IN PLANT SCIENCE 9 Article 1936 2019 (External fulltext)
- PROCEEDINGS OF THE NAS OF THE USA 2019 (External fulltext)
Mutations in the HvDWARF, HvCPD and HvBRI1 genes – involved in brassinosteroid biosynthesis/signalling – altered photosynthetic efficiency, hormonal homeostasis and tolerance to high/low temperatures in barley.JOURNAL OF PLANT GROWTH REGULATION 2019
Changes in content of steroid regulators during cold hardening of winter wheat - Steroid physiological/biochemical activity and impact on frost resistancePLANT PHYSIOLOGY AND BIOCHEMISTRY 2019
- CURRENT BIOLOGY 29 2743-2750.e5 2019 (External fulltext)